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Randy Johnson goes for No. 300 tonight

For the past 21 years, Randy Johnson has been one of the most dominating pitchers in baseball. Tonight, he'll attempt to become the 23rd pitcher to reach 300 career victories when he pitches against the Nationals in Washington.

Randy Johnson will attempt to become the 23rd pitcher in MLB history to reach 300 wins But if he isn't able to accomplish the feat this week, his next attempt will come against the Marlins at Land Shark Stadium next Monday night.

Johnson, 45, is 4-4 with a 5.71 ERA this season. He began his career with Montreal Expos and has pitched for the Diamondbacks, Astros, Mariners and Yankees. He is 4-3 with a 2.99 ERA against the Nationals since they moved over from Montreal.

His career numbers against the Marlins are even scarier. He's 8-1 in 13 career starts against the Fish with a 1.78 ERA, 117 Ks and just 23 walks.

I wrote about Johnson and his chase for 300 in my Sunday baseball column and whether or not he'll be the last pitcher in baseball to achieve the feat. Tim Brown of Yahoo Sports wrote an interesting piece on Johnson's road to 300 and how much his former teammates might or might not be happy when he reaches the record.

Oddly enough, if The Big Unit doesn't get the job done against the Nationals, he could pitch against Marlins rookie left-hander Sean West on Monday. West, who is getting the start tonight versus the Brewers, had the same agent as Johnson -- former MLB pitcher Bobby Witt. West (6-8, 240) was nicknamed 'The Little Unit' by Witt before the Marlins drafted him in the first round four years ago. West said Johnson is the pitcher he looks up to most.